Yes, combining multiple enzyme types (e.g., protease, lipase, and amylase) in a single formula can be effective, as long as:

• The enzymes complement each other without interfering or degrading one another.

• The pH range of each enzyme overlaps appropriately to ensure activity in different parts of the digestive tract.

• Enzymes are sourced from stable, high-quality providers to avoid issues of degradation when mixed.

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To maintain enzyme stability and efficacy:

• Choose appropriate delivery forms, like enteric-coated capsules, to protect enzymes from stomach acid.

• Use moisture protection strategies, such as adding desiccants to packaging or using encapsulation technologies, to prevent enzyme degradation.

• Avoid ingredients that may inactivate enzymes, such as certain preservatives, or use stabilizers to ensure enzymes remain active throughout the product’s shelf life.

• Conduct stability testing under various environmental conditions to ensure long-term enzyme activity.

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When choosing enzymes for your supplement, consider the following:

• Target function (e.g., digestion, inflammation, immune support)

• Enzyme types based on the macronutrients they break down (e.g., protease for proteins, amylase for carbs, lipase for fats).

• Source of enzymes (plant-based, microbial, or animal-derived), ensuring they align with your target audience (e.g., vegan-friendly).

• pH stability to ensure enzymes remain active through various parts of the digestive system.

• Potency (measured in activity units like HUT for protease or ALU for lactase) to achieve the desired effect.